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Application Note
Quantifying CpG methylation using MS-HRM qPCR
DNA methylation is an epigenetic process through which nucleobases (mainly cytosines) are modified by the addition of a methyl group.
This mechanism has essential roles in cellular processes including regulation of gene expression, development, and disease. In this application note we describe a workflow for the analysis of DNA methylation in specific loci using methylation-sensitive high-resolution melting (MS-HRM) qPCR.
Product Launch
VeriFi™ Library Amplification Mix
A specially formulated 2x ready mix designed for NGS library amplification with reduced GC bias.
VeriFi™ Library Amplification Mix combines the powerful proofreading performance of VeriFi Hot Start Polymerase with a greatly reduced GC-dependent bias to push the limits of NGS data quality when sequencing ever longer and more complex targets.
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